Dr. Kong is a molecular parasitologist interested in fundamental questions of how and why parasites adapt to the sophisticated mammalian immune system and how the parasite exploit their bioactive systems to ensure their long-term survival in the unfavorable host environments. His laboratory focuses on the most complex parasites to invade the body, multicellular helminths, which cause fatal outcome in the victims. The central questions his group addresses are (i) which molecules are invoked specific antibody responses by manipulating the host immune system. (ii) what parasite molecules are responsible for adaptation into the hosts? Most of his major publication dealt with these issues. His group has deep interests in characterizing biological and pathophysiological roles of antioxidants and proteolytic enzymes.
학력
(Ph.D.): Chung-Ang University, School of Medicine, Seoul, Korea
약력/경력
Internship, Chung-Ang University Medical Center, Seoul, Korea
Senior Research Scientist, Biomedical Research Center, KIST, Seoul, Korea
Visiting Scholar, Gifu University School of Medicine, Gifu, Japan
Visiting Scientist, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
Professor, Sungkyunkwan University School of Medicine, Suwon, Korea
학술지 논문
(2023)
Omega-Class Glutathione Transferases Protect DNA from Oxidative Stress in Pathogenic Helminth Reproductive Cells.
ANTIOXIDANTS.
12,
3
(2022)
Cerebral paragonimiasis: Clinicoradiological features and serodiagnosis using recombinant yolk ferritin.
PLOS NEGLECTED TROPICAL DISEASES.
16,
3
(2022)
Echinococcus granulosus Protoscolex DM9 Protein Shows High Potential for Serodiagnosis of Alveolar Echinococcosis.
KOREAN JOURNAL OF PARASITOLOGY.
60,
1
(2021)
Omega-Class Glutathione Transferases of Carcinogenic Liver Fluke, Clonorchis sinensis, Modulate Apoptosis and Differentiation of Host Cholangiocytes.
ANTIOXIDANTS.
10,
7
(2021)
Spectrum of pleuropulmonary paragonimiasis: An analysis of 685 cases diagnosed over 22 years.
JOURNAL OF INFECTION.
82,
1
(2019)
Survey of echinococcoses in southeastern Qinghai Province, China, and serodiagnostic insights of recombinant Echinococcus granulosus antigen B isoforms.
PARASITES & VECTORS.
12,
(2019)
Clonorchis sinensis omega-class glutathione transferases are reliable biomarkers for serodiagnosis of clonorchiasis and opisthorchiasis.
CLINICAL MICROBIOLOGY AND INFECTION.
25,
1
(2018)
Human Sparganosis in Korea.
JOURNAL OF KOREAN MEDICAL SCIENCE.
33,
44
(2018)
Comparison of Secretome Profile of Pathogenic and Non-Pathogenic Entamoeba histolytica.
PROTEOMICS.
18,
7
(2017)
Comparison of Echinococcus multilocularis and Echinococcus granulosus hydatid fluid proteome provides molecular strategies for specialized host-parasite interactions.
ONCOTARGET.
8,
57
(2017)
Recurrent emergence of structural variants of LTR retrotransposon CsRn1 evolving novel expression strategy and their selective expansion in a carcinogenic liver fluke, Clonorchis sinensis.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY.
214,
(2017)
Biochemical Characterization of Echinococcus multilocularis Antigen B3 Reveals Insight into Adaptation and Maintenance of Parasitic Homeostasis at the Host-Parasite Interface.
JOURNAL OF PROTEOME RESEARCH.
16,
2
(2016)
Spatiotemporal Expression Patterns and Antibody Reactivity of Taeniidae Endophilin B1.
JOURNAL OF CLINICAL MICROBIOLOGY.
54,
10
(2016)
Medical treatment of tropical parasitic diseases.
대한의사협회지.
59,
9
(2016)
Clonorchis sinensis omega-class glutathione transferases play major roles in the protection of the reproductive system during maturation and the response to oxidative stress.
PARASITES & VECTORS.
9,
(2016)
Functionally Expression of Metalloproteinase in Taenia solium Metacestode and Its Evaluation for Serodiagnosis of Cysticercosis.
IRANIAN JOURNAL OF PARASITOLOGY.
11,
1
(2016)
Phylogenetic characterization of Clonorchis sinensis proteins homologous to the sigma-class glutathione transferase and their differential expression profiles.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY.
206,
1-2
(2015)
An Echinococcus multilocularis Antigen B3 Proteoform That Shows Specific Antibody Responses to Active-Stage Alveolar Echinococcosis.
JOURNAL OF CLINICAL MICROBIOLOGY.
53,
10
(2015)
Egg-specific expression of protein with DNA methyltransferase activity in the biocarcinogenic liver fluke Clonorchis sinensis.
PARASITOLOGY.
142,
9
단행본
(2020)
Clinival cases in tropical medicine.
Elsevier.
공동
(2015)
Biology of Foodborne Parasites.
CRC Press.
주저자
(2013)
해리슨 내과학.
도서출판 MIP.
단독
(2009)
Mobile Genetic Elements in Metazoan Parasites.
Landes Bioscience.
주저자
(2006)
Harrison 내과학.
MIP.
단독
(2005)
Retrotransposons in the genomes of digenean parasitic trematodes, Clonorchis sinensis and Paragonimus westermani. In Mobile Genetic Elements in Metazoan Parasites (ed. Brindley, P.).
Landes Bioscience.
단독
(2003)
Harrison's Principles of INternal Medicine.
도서출판 MIP.
단독
특허/프로그램
A recombinant antigen of Taenia solium metacestodes.
6589752.
20030608.
미국
수상/공훈
Member, American Society for Microbiologists
Fellow, Royal Society of Tropical Medicine and Hygiene
Member, National Academy of Medicine of Korea (NAMOK), Republic of Korea.
학술회의논문
(2019)
Cloorchis sinensis omega-class glutathione transferases are reliable biomarkers for serodiagnosis of clonorchiasis and opisthorchiasis.
대한기생충학/열대의학회 제 61회 총회 학술대회.
대한민국
(2018)
Biological roles of antioxidant glutathione transferases of Clonorchis sinensis.
14th International Conference on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases.
스페인
(2018)
Comparison of hydatid fluid proteome of Echinococcus multilocularis and E. granulosus and moleculuar properties of EmAgB3.
14th International Conference on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases.
스페인
(2017)
Biological roles of Echinococcus multilocularis antigen B3 at the host-parasite interface.
NTD Asia 2017.
태국
(2016)
Clonorchis sinensis omega-class glutathione transferaseplay major roles in the protection of reproductive system during maturation and the response to oxidative stress.
대한기생충학,열대의학 제58회 학술대회.
대한민국
(2016)
Expression patterns and antibody reactivity of Taeniidae endophilin B1.
대한기생충학,열대의학회 제 58최 학술대.
미국
(2016)
Sigma-class glutathione transferases encompassed by Clonorchis sinensis genome reveal differential expression profiles during maturation of the parasite and in response to oxidative stresses.
NTDASIA2016.
태국
(2016)
Taenia solium metacestode fasciclin-like protein is reactive with sera of inactive neurocysticercosis.
NTDASAIA2016.
태국
(2015)
다방포충증 경과에 따른 EmAgB3 항원 반응 특이성 및 EmAgB3 복합체 구조 분석.
대한 기생충학 열대의학회 학술대회.
대한민국
(2015)
간흡충에서 분리한 DNA methytransferase (CsDNMT2)의 생화학적 활성 및 발현 연구.
대한 기생충학 열대의학회 학술대회.
대한민국
(2014)
이질아메바 병원성과 비병원성 균주 분비/배설 단백체 비교 분석.
대한기생충학열대의학회 제56차 학술발표대회.
대한민국
(2014)
간흡충 omega-type glutathione transferase의 생화학적 특성.
대한기생충학열대의학회 제 56차 학술대회.
대한민국
(2014)
다방포충증 혈청 진단을 위한 EmAgB3 항원 특이성.
대한기생충학열대의학회 제 56차 학술대회.
대한민국
(2014)
Alteration of immunoproteome profile of Echinococcus granulosus hydatid fluid with progression of cystic echinococcosis.
13th International Congress of Parasitology.
멕시코
(2014)
Taenia solium metacestode fasciclin-like protein is reactive with sera of inactive neurocysticercosis.
13th International Congress of Parasitology.
멕시코
(2014)
Biochemical properties of two omega-type glutathione transferases of Clonorchis sinensis.
13th International Congress of Parasitology.
멕시코
(2014)
Comparison of secretorm profile of Entamoeba histolytica pathogenic and non-pathogenic strain.
13th International Congress of Parasitology.
멕시코
(2013)
Proteomic characterization and of immunoproteome profile of Echinococcus granulosus hydatid fluid following disease progression of cystic echinococcosis.
제55차 대한기생충학 열대의학 학술대회.
대한민국
(2013)
중국 칭하이성 쳉두지역 포충증 감염 조사.
제55차 대한기생충학 열대의학 학술대회.
대한민국
(2013)
Calpain-mediated o-deglcanacylation is requied for cell death of human hepatocytes induced by pathogenic Entamoeba histolytica.
제17차 아베마 학회.
멕시코
